20,000+m²
Across two plants
BIOSPHERE-AI
Capabilities & Services
Manufacturing, brand incubation, supply-chain integration and global delivery — buy any one capability on its own, or hand us the whole job. Behind it: 15 smart production lines in Guangzhou (20,000+ m² of land across both sites), 13,000+ proven formulations and a Class-100,000 GMP cleanroom.
What manufacturing capabilities does BIOSPHERE-AI offer brands?
Guangzhou Biosphere Cosmetics is an AI-driven herbal beauty manufacturing platform: 20,000+ m² of land across two sites in Guangzhou and Indonesia, with all production in Guangzhou, 15 automated lines and a Class-100,000 GMP cleanroom; daily capacity above 500,000 sheet masks and 300,000 lotion/cream units. A library of 13,000+ proven formulations supports 3–7 day sampling. GMPC, ISO 22716 and HALAL certification plus US FDA facility registration and EU CPNP notification experience cover market entry across Europe, the Americas, Southeast Asia and the Middle East. We take on OEM, ODM and full brand incubation.
- How do OEM and ODM work here?
- OEM: you bring the formula or standard, we manufacture to it under full quality control. ODM: we shortlist from 13,000+ formulations on file to match your positioning, sample in 3–7 days, then move to pilot and mass production. Only an idea? Start with brand incubation.
- How is MOQ calculated?
- By format and packaging combination: mature formats run standard MOQs (marked on every format in the catalogue); special packaging or custom formulas get a clear threshold at the scoping stage — one quotation, nothing hidden.
- How long does sampling take?
- 3–7 days for mature formulation directions. Experience and stability screening starts at the sample stage, so what you approve is what scales.
- Who prepares export certification and documents?
- The factory holds GMPC, ISO 22716 (DEKRA) and HALAL certification, with US FDA facility registration and EU CPNP notification experience; COA, MSDS and other export documents ship with the order.
- Can I buy just one capability?
- Yes. Manufacturing, brand incubation, supply-chain integration and global delivery are priced independently — brands with a mature supply chain place manufacturing-only orders; new brands can hand over the whole job.
- Where are Southeast Asia orders produced?
- All orders are currently produced and shipped from Guangzhou. The Tangerang site in Indonesia is at the investment stage and not yet in production; HALAL and local compliance for Southeast Asia and the Middle East are handled from Guangzhou.
CAPABILITIES
Three types of work we take on
From "formulas ready for mass production" to "just an idea", the starting point changes the path.
- ManufacturingFour categories, 15 flexible lines
- Brand incubationFormula, packaging and filings from zero
- Packaging developmentStructural sampling + compatibility testing
- Formula replicationBenchmark reverse-engineering, made compliant
- Testing servicesStability / Microbial / Compatibility
- Export complianceRegistrations and shipping docs per market
Six core capabilities, item by item
From cultivation to delivery, every link in the chain is held in-house — that is what separates herbal AI manufacturing from ordinary contract work.
Cultivation bases
Dual-source raw materials: Eastern herbs and Amazonian botanicals.
- 20+ partner mountain cultivation bases
- Bijie, Kashgar and Qingyuan growing regions
- Graded harvesting · residue traceability ledger
Classical formula research
Millennia of herbal knowledge, validated by modern science.
- 20,000+ classical formula texts digitised
- Classical wisdom × modern efficacy validation
Biosynthesis
Fermentation and cold flash extraction, 10–20× activity.
- Rare ginsenoside activity up 10–20×
- Pesticide residues degraded 90%+
- rhCOLL recombinant collagen
AI product selection
Trend insight from large-scale data.
- Data-driven product briefs
- Lower trial-and-error cost on launches
Smart traceability
Every unit traceable from raw material to finished good.
- One code per unit
- Cultivation—extraction—filling, all logged
Smart manufacturing
15 smart lines, flexible across batch sizes.
- Class-100,000 GMP cleanroom
- 500k masks / 300k lotion-cream units daily
15lines
Automated production
13,000+
Proven formulations
300+
Strategic suppliers
Technology moats: the evidence
More than production lines — three in-house technologies set the ceiling on formula activity.
- Herbal fermentation: rare ginsenoside activity up 10–20×
- Targeted microbes biotransform plant material, breaking cell walls to release and convert actives; pesticide residues degraded by 90%+.In-house fermentation conversion system
- Cold flash extraction: 95%+ retention of heat-sensitive actives
- Extraction at 0–10℃ with high-efficiency solvent systems and physical-field assisted mass transfer; extraction efficiency up 40%.Cold flash extraction process
- Biosynthesis: rhCOLL recombinant humanised collagen
- High-activity functional ingredients built with synthetic-biology methods — the flagship result of joint research.Jinan University research partnership
Six-step smart production loop
Every batch runs the same loop: traceable raw material in, scan-to-verify finished goods out.
- 01
Raw-material tracing
Direct from cultivation bases; batch data traceable end to end.
- 02
Cold extraction
0–10℃ extraction protects heat-sensitive actives.
- 03
AI dosing
Algorithmic dosing control for batch-to-batch consistency.
- 04
In-line inspection
Real-time monitoring with automatic deviation alerts.
- 05
Quality testing
Four-property testing plus ten safety gates before release.
- 06
Finished-goods traceability
A unique code per unit; scan to verify the whole chain.
HOW WE WORK
From first contact to mass production
Different starting points, different routes — but every order passes all six gates.
1.0SCOPE
Scoping & regulatory pre-check
Capacity match plus target-market regulatory pre-check — if it cannot be done, we say so up front.
2.0FORMULA
Formula selection
Shortlist from 13,000+ proven formulations or customise to your brief; four-property test criteria are set here, not later.
3.0SAMPLE
Rapid sampling
3–7 days for mature directions; experience and stability screening starts at the sample stage.
4.0PILOT
Pilot scale-up
Formula review, pilot batches and full-cycle stability — most sample-to-scale failures die from skipping this step.
5.0SCALE
Mass production & inspection
Class-100,000 GMP cleanroom, in-line patrols plus finished-goods testing, ten safety gates before release.
6.0SHIP
Delivery & traceability
Export documents ship with the order; every unit carries a unique traceability code.
DUAL BASES
Made in Guangzhou · Indonesia in development
Production sits in Guangzhou: 15 smart lines and a Class-100,000 GMP cleanroom. The Tangerang site in Indonesia is an investment in development and is not yet in production.
Headquarters
Guangzhou Headquarters
Guangzhou · China
- Main capability
- Global R&D and brand-service centre; 15 modern smart lines; 10,000+ m² smart warehousing
- 规范
- Class-100,000 GMP · GMPC · ISO 22716
Overseas investment site
Tangerang site, Indonesia (in development)
Indonesia
- Main capability
- Investment stage — not yet in production. Southeast Asia and Middle East orders are currently produced and shipped from Guangzhou, with HALAL and local compliance handled there.
- 规范
- In development — no separate certification yet
20,000+ m² of land across both sites; certification and testing details under Quality & Compliance. All orders are currently produced in Guangzhou.
Certification & market access
Certificates are entry tickets, not wall decoration: GMPC and ISO 22716 (DEKRA) clear factory audits for Western orders, HALAL opens the Middle East and Indonesia, FDA registration and CPNP notification support US and EU listings.
- GMPCGood Manufacturing Practice of Cosmetics (DEKRA)
- ISO 22716:2007Cosmetics GMP international standard (DEKRA)
- HALALHalal certification for Middle East and Indonesia
- FDAUS FDA cosmetic facility registration
- CPNPEU cosmetic product notification
- SGSThird-party testing reports
- CEEU conformity marking
- Invention patentsPatents on core technology
Formula security & confidentiality
A brand’s deepest worry is not capacity — it is whether a hero formula leaks to a competitor. Three principles, in writing:
- One formula, one client
- A formula customised or adapted for you serves you alone — never reused or repackaged for anyone else.Contract clause
- NDA before sampling
- Confidentiality agreements come before samples; formulas, packaging plans and business information are segregated per client.NDA process
- Technology independence
- Fermentation, cold flash extraction and biosynthesis are in-house systems — no reliance on client input, no lock-in created.In-house technology
What we don't take on
One-off orders
Every project starts with capacity matching and regulatory pre-check. If these two steps don't work out, the product won't reach market. We'd rather be upfront than take the order and then tell you it can't be filed.
Not sure which category you fall into?
Send us what you already have — a formula, a sample, or just a one-line idea. We can work out the next step.