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Neutrogena advanced acne serum

Neutrogena neutrogena advanced acne serum lists 18 ingredients on its label, 18 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Water
  2. Glycolic Acid
  3. Propylene Glycol
  4. Dimethicone
  5. Mandelic Acid
  6. Gluconolactone
  7. Sodium Hydroxide
  8. Neopentyl Glycol Diheptanoate
  9. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  10. Polyacrylate Crosspolymer-6
  11. Salicylic Acid
  12. Dimethicone Crosspolymer
  13. Disodium EDTA
  14. Dipropylene Glycol
  15. Ethyl Linalool
  16. Methyldihydrojasmonate
  17. Methyl Anthranilate
  18. 3-Hexenol

Highlights

Free of alcoholFree of parabensFree of sulfatesFree of mineral oilFree of formaldehyde releasersContains siliconesContains EU-26 allergensContains fragranceContains essential oils

Formulation view Aqueous serum with high-concentration glycolic and mandelic acids, plus salicylic acid for exfoliation. Dimethicone provides slip, polymers provide viscosity. pH adjusted with sodium hydroxide. Hydrated with polyols. Suitable for tolerant skin. Factory view: Multi-acid blending requires strict pH control to manage irritation risks.

Key ingredients

ANTIPLAQUE
Water
BUFFERING
Glycolic AcidSodium Hydroxide
HUMECTANT
Propylene Glycol
ANTIFOAMING
Dimethicone
ANTIMICROBIAL
Mandelic Acid
CHELATING
Gluconolactone
SKIN CONDITIONING - EMOLLIENT
Neopentyl Glycol Diheptanoate

Other ingredients

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerPolyacrylate Crosspolymer-6Salicylic AcidDimethicone CrosspolymerDisodium EDTADipropylene GlycolEthyl LinaloolMethyldihydrojasmonateMethyl Anthranilate3-Hexenol

Skim through

IngredientWhat it doesIrr. · Com.Rating
WaterANTIPLAQUE, SKIN CONDITIONING, SOLVENT0 · 0Green
Glycolic AcidBUFFERING2 · 0Green
Propylene GlycolHUMECTANT, FRAGRANCE, SOLVENT, VISCOSITY CONTROLLING, SKIN CONDITIONING - HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS1 · 0Green
DimethiconeANTIFOAMING, SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING, SKIN PROTECTING0 · 0Green
Mandelic AcidANTIMICROBIAL2 · 0Green
GluconolactoneCHELATING, SKIN CONDITIONING2 · 1Green
Sodium HydroxideBUFFERING, DENATURANT · 限制 III/15a3 · –Green
Neopentyl Glycol DiheptanoateSKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING0 · –Green
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerEMULSION STABILISING, VISCOSITY CONTROLLING0 · 0Green
Polyacrylate Crosspolymer-6EMULSION STABILISING, VISCOSITY CONTROLLING0 · 0Green
Salicylic AcidANTI-SEBORRHEIC, HAIR CONDITIONING, KERATOLYTIC, FRAGRANCE, PRESERVATIVE, SKIN CONDITIONING · 限制 III/98 V/32 · 0Yellow
Dimethicone CrosspolymerEMULSION STABILISING, HAIR FIXING, VISCOSITY CONTROLLING0 · 0Green
Disodium EDTACHELATING, VISCOSITY CONTROLLING0 · 0Green
Dipropylene GlycolFRAGRANCE, SOLVENT, VISCOSITY CONTROLLING, PERFUMING0 · 0Green
Ethyl LinaloolFRAGRANCE, PERFUMING0 · 0Green
MethyldihydrojasmonateFRAGRANCE0 · 0Green
Methyl AnthranilateFRAGRANCE0 · 0Green
3-HexenolFRAGRANCE, SKIN CONDITIONING, PERFUMING0 · 0Green

Ingredients explained

Water
Primary solvent and base; requires preservative system to prevent microbial growth
Glycolic Acid
Glycolic acid for exfoliation; requires buffering at concentrations >10%, avoid combination with other acids.
Propylene Glycol
Polyol humectant at 3-10%; hygroscopic, slight tackiness, mild irritation at high conc., verify preservative efficacy, no allergen.
Dimethicone
Silicone occlusive at 1–5%; provides smooth feel, non-penetrating, suitable for sensitive skin
Mandelic Acid
Alpha-hydroxy acid for exfoliation and antibacterial effects; mild penetration, less photosensitivity than other AHAs
Gluconolactone
Multifunctional agent for chelation and permeation; acidic, may irritate at high levels, buffer recommended.
Sodium Hydroxide
Strong base neutralizer for pH adjustment; handle with extreme care
Neopentyl Glycol Diheptanoate
Light emollient ester, non-greasy, improves product spreadability.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
High-molecular-weight thickener and emulsion stabilizer; requires electrolytes or acid adjustment near isoelectric point for optimal performance.
Polyacrylate Crosspolymer-6
Water-soluble thickener; requires neutralizer, performs best at pH 5–7
Salicylic Acid
Lipophilic BHA at 0.5-2%; exfoliant/sebum control, irritation/sensitization at high conc., photosensitivity (SPF needed), avoid sensitive/pregnant.
Dimethicone Crosspolymer
Crosslinked silicone polymer providing silkiness and viscosity control; for hair and skin; inert but hard to biodegrade.
Disodium EDTA
Chelating agent at 0.05–0.5%; sequesters metal ions for stability, boosts preservative efficacy
Dipropylene Glycol
Solvent for essential oils; better humectancy than PEG
Ethyl Linalool
Fragrance ingredient providing floral notes; listed as one of EU 26 allergens, labeling required.
Methyldihydrojasmonate
Methyl dihydrojasmonate, jasmine accord; synthetic fragrance, potential allergen.
Methyl Anthranilate
Jasmine-like fragrance, photosensitizing; avoid sun exposure combination, comply with regulatory limits.
3-Hexenol
Plant essential oil component with green scent; fragrance and potential allergen, control concentration.

Source: full ingredient list published on the product label, collected 2026-09-17. Ratings are our internal reading, not a regulatory conclusion. · Product page

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