30+
Senior R&D specialists
BIOSPHERE-AI
Research & innovation
R&D is not stacking actives; it is finding the balance between efficacy and stability inside the regulatory envelope.
R&D is not stacking actives; it is finding the balance between efficacy and stability inside the regulatory envelope.
Every claim needs a matching test plan. If a direction cannot be substantiated, we say so.
13,000+
Proven formulations on file
3
In-house routes: fermentation · extraction · biosynthesis
20,000+
Classical formula texts digitised
In-house technology: measured results on three routes
An R&D page should carry more than adjectives — three in-house routes, each with verifiable numbers and their source.
- Fermentation route: rare ginsenoside activity up 10–20×
- Targeted microbes break down plant cell walls to release and convert actives; the same route degrades pesticide residues by 90%+ — activity and safety rise together.In-house fermentation system
- Cold flash extraction route: 95%+ retention of heat-sensitive actives
- A 0–10℃ extraction window protects sensitive actives while physical-field assisted mass transfer lifts efficiency another 40% — retention and speed are not a trade-off.Cold flash extraction process
- Biosynthesis route: rhCOLL recombinant humanised collagen
- High-activity functional ingredients built with synthetic biology; the joint programme with Jinan University is the academic base of this route.Jinan University partnership
LAB
Laboratory & Testing Capabilities
Stability, compatibility, microbiological and preservative challenge tests are performed in our in-house laboratory. Human efficacy and safety tests are outsourced to third-party institutions.
- Formulation LabCustom Development & Reverse Engineering
- Analytical TestingActive Ingredients & Physicochemical Parameters
- Microbiological TestingTotal Count / Pathogens
- Stability TestingHigh Temperature · Light Exposure · Thermal Cycling
R&D Team
Formulators and testing engineers work in the same room
When a formula is revised, testing can be scheduled the same day; when testing flags an issue, the formulator turns around and makes the change. This is not a small efficiency gain—sample turnaround in 3–7 days comes from eliminating the wait between separate companies.
View formulation technologyHERITAGE
Ancient formula research: the combination logic draws on historical texts, while the final formulation follows current regulations and laboratory data.
We have compiled 213 facial balm, washing-bean, and facial cream recipes recorded in classical works such as Waitai Miyao as a source of formulation ideas. This is research, not reproduction — historical records do not constitute efficacy claims.
Qianjin Facial Cream Formula
Waitai Miyao · combination of Qingmuxiang / Baizhi / Fuling
Yannian Facial Balm Formula
Waitai Miyao · combination of Baizhu / Weirui / Mulanpi
Guangji Washing-Bean Formula
Waitai Miyao · combination of Baizhi / Bailian / Tianmendong
Qianjin Washing-Bean Formula
Waitai Miyao · combination of Taohua / Yingtaohua / Bailianhua
Baifuzi Cream Formula
Waitai Miyao · combination of Baifuzi / Dingxiang / Shanglu
Zhuyi Moisturizing Formula
Waitai Miyao · combination of Gualouzi / Taoren / Wujingzi
R&D Principles
Every claim on the product must be backed by a corresponding test plan.
If a direction cannot be substantiated, we say so directly instead of taking the order first and figuring it out later. R&D is not about piling on active ingredients; it is about finding the balance between efficacy and stability within what regulations allow.
Have an existing formula to replicate, or only a direction so far?
Both work. If you have a formula, we handle reverse engineering and compliance adjustment. If you only have a direction, we work backward from category positioning to a workable formula brief.