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neostrata Skin Active Dermal Replenishment

neostrata Neostrata Skin Active Dermal Replenishment lists 51 ingredients on its label, 47 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Aqua
  2. Glycerin
  3. Maltobionic Acid
  4. Acetyl Glucosamine
  5. Octyldodecyl Neopentanoate
  6. Steareth-2
  7. C12-15 Alkyl Benzoate
  8. Butyrospermum Parkii Butter
  9. Octyldodecanol
  10. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  11. Isostearic Acid
  12. Cyclopentasiloxane
  13. Acetyl Tyrosinamide
  14. Saccharide Isomerate
  15. Cyclohexasiloxane
  16. Palmitoyl Tripeptide-1
  17. Palmitoyl Tetrapeptide-7
  18. Vitis Vinifera Seed Extract
  19. Sodium PCA
  20. Serine
  21. Glycine
  22. Alanine
  23. Lysine
  24. Arginine
  25. Threonine
  26. Proline
  27. Cetyl Alcohol
  28. Propylene Glycol
  29. Betaine
  30. Sorbitol
  31. Isopropyl Myristate
  32. Glutamic Acid
  33. Butylene Glycol
  34. Polysorbate 60
  35. Sorbitan Isostearate
  36. Carbomer
  37. Polysorbate 20
  38. Steareth-20
  39. Ammonium Hydroxide
  40. Disodium EDTA
  41. Caprylyl Glycol
  42. Sodium Bisulfite
  43. Xanthan Gum
  44. Phenoxyethanol
  45. Chlorphenesin
  46. Methyldihydrojasmonate
  47. Isobutyl Methyl Tetrahydropyranol
  48. Ethylene Brassylate
  49. Methyl Decenol
  50. Ci 14700
  51. Ci 19140

Highlights

Free of alcoholFree of parabensFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains siliconesContains fragranceContains PEGContains EU-26 allergens

Key ingredients

SOLVENT
Aqua
DENATURANT
Glycerin
SKIN CONDITIONING
Acetyl GlucosamineButyrospermum Parkii Butter
SKIN CONDITIONING - EMOLLIENT
Octyldodecyl NeopentanoateOctyldodecanol
ANTIMICROBIAL
C12-15 Alkyl Benzoate
EMULSION STABILISING
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Other ingredients

Maltobionic AcidSteareth-2Isostearic AcidCyclopentasiloxaneAcetyl TyrosinamideSaccharide IsomerateCyclohexasiloxanePalmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7Vitis Vinifera Seed ExtractSodium PCASerineGlycineAlanineLysineArginineThreonineProlineCetyl AlcoholPropylene GlycolBetaineSorbitolIsopropyl MyristateGlutamic AcidButylene GlycolPolysorbate 60Sorbitan IsostearateCarbomerPolysorbate 20Steareth-20Ammonium HydroxideDisodium EDTACaprylyl GlycolSodium BisulfiteXanthan GumPhenoxyethanolChlorphenesinMethyldihydrojasmonateIsobutyl Methyl TetrahydropyranolEthylene BrassylateMethyl DecenolCi 14700Ci 19140

Skim through

IngredientWhat it doesIrr. · Com.Rating
AquaSOLVENT0 · 0Green
GlycerinDENATURANT, HAIR CONDITIONING, HUMECTANT, ORAL CARE, SKIN PROTECTING, SOLVENT, VISCOSITY CONTROLLING, PERFUMING, FRAGRANCE, SKIN CONDITIONING - HUMECTANT0 · 0Green
Maltobionic AcidNot decoded yet
Acetyl GlucosamineSKIN CONDITIONING0 · 0Green
Octyldodecyl NeopentanoateSKIN CONDITIONING - EMOLLIENT0 · 0Green
Steareth-2Not decoded yet
C12-15 Alkyl BenzoateANTIMICROBIAL, SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING0 · 2Green
Butyrospermum Parkii ButterSKIN CONDITIONING, VISCOSITY CONTROLLING0 · 1Green
OctyldodecanolSKIN CONDITIONING - EMOLLIENT, FRAGRANCE, SOLVENT, PERFUMING0 · 0Green
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerEMULSION STABILISING, VISCOSITY CONTROLLING0 · 0Green
Isostearic AcidBINDING, CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - CLEANSING0 · 2Green
CyclopentasiloxaneSKIN CONDITIONING - EMOLLIENT, HAIR CONDITIONING, SKIN CONDITIONING, SOLVENT0 · 0Green
Acetyl TyrosinamideNot decoded yet
Saccharide IsomerateHUMECTANT0 · –Green
CyclohexasiloxaneSKIN CONDITIONING - EMOLLIENT, HAIR CONDITIONING, SOLVENT0 · 0Green
Palmitoyl Tripeptide-1SKIN CONDITIONING0 · 0Green
Palmitoyl Tetrapeptide-7SKIN CONDITIONING - MISCELLANEOUS0 · 0Green
Vitis Vinifera Seed ExtractANTI-SEBORRHEIC, ANTIMICROBIAL, ANTIOXIDANT, ORAL CARE, SKIN PROTECTING, UV ABSORBER0 · 0Green
Sodium PCAANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING– · 0Green
SerineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · –Green
GlycineANTISTATIC, BUFFERING, HAIR CONDITIONING, SKIN CONDITIONING0 · –Green
AlanineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · 0Green
LysineANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING0 · 0Green
ArginineANTISTATIC, HAIR CONDITIONING, FRAGRANCE, SKIN CONDITIONING0 · 0Green
ThreonineANTISTATIC, HAIR CONDITIONING, HAIR WAVING OR STRAIGHTENING0 · 0Green
ProlineHAIR CONDITIONING, SKIN CONDITIONING0 · 0Green
Cetyl AlcoholSKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING, EMULSION STABILISING, SURFACTANT - FOAM BOOSTING, FRAGRANCE, OPACIFYING, SURFACTANT - CLEANSING, VISCOSITY CONTROLLING1 · 1Green
Propylene GlycolHUMECTANT, FRAGRANCE, SOLVENT, VISCOSITY CONTROLLING, SKIN CONDITIONING - HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS1 · 0Green
BetaineHAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING - HUMECTANT0 · 0Green
SorbitolHUMECTANT, FRAGRANCE, SKIN CONDITIONING, PERFUMING0 · 0Green
Isopropyl MyristateBINDING, SKIN CONDITIONING - EMOLLIENT, FRAGRANCE, PERFUMING0 · 5Green
Glutamic AcidANTISTATIC, HAIR CONDITIONING, HUMECTANT0 · 0Green
Butylene GlycolHUMECTANT, FRAGRANCE, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING0 · 0Green
Polysorbate 60SURFACTANT - EMULSIFYING, SURFACTANT - CLEANSING1 · –Green
Sorbitan IsostearateSURFACTANT - EMULSIFYING0 · 1Green
CarbomerEMULSION STABILISING, GEL FORMING, VISCOSITY CONTROLLING0 · 0Green
Polysorbate 20SURFACTANT - EMULSIFYING, SURFACTANT - CLEANSING0 · 0Green
Steareth-20Not decoded yet
Ammonium HydroxideBUFFERING, DENATURANT · 限制 III/45 · 0Green
Disodium EDTACHELATING, VISCOSITY CONTROLLING0 · 0Green
Caprylyl GlycolDEODORANT, SKIN CONDITIONING - EMOLLIENT, HAIR CONDITIONING, SKIN CONDITIONING0 · 0Green
Sodium BisulfiteANTIOXIDANT, HAIR WAVING OR STRAIGHTENING, PRESERVATIVE, REDUCING · 限制 III/99 V/93 · –Yellow
Xanthan GumBINDING, SURFACTANT - EMULSIFYING, EMULSION STABILISING, GEL FORMING, SKIN CONDITIONING, SURFACTANT - CLEANSING, VISCOSITY CONTROLLING0 · 0Green
PhenoxyethanolANTIMICROBIAL, PRESERVATIVE · 限制 V/291 · 0Yellow
ChlorphenesinANTIMICROBIAL, PRESERVATIVE · 限制 V/501 · 0Yellow
MethyldihydrojasmonateFRAGRANCE0 · 0Green
Isobutyl Methyl TetrahydropyranolFRAGRANCEGreen
Ethylene BrassylateFRAGRANCE, TONIC1 · 0Green
Methyl DecenolFRAGRANCE, SKIN CONDITIONING, PERFUMING0 · –Green
Ci 14700COLORANT · 限制 IV/18 ( CI 14700) II/1341 (Ponceau SX; CI 14700: when used as a substance in hair dye products)Green
Ci 19140COLORANT, HAIR DYEING · 限制 IV/44 (CI 19140) III/189 (Acid Yellow 23; Acid Yellow 23 Aluminum lake)0 · 0Green

Ingredients explained

Aqua
Solvent, main base; microbial control is critical
Glycerin
Workhorse humectant at 3–10%; tacky at high levels, pair with occlusives
Maltobionic Acid
Not decoded yet
Acetyl Glucosamine
Glycosaminoglycan precursor supporting skin hydration and elasticity; highly biocompatible.
Octyldodecyl Neopentanoate
Ester emollient; light oil feel; low irrit, low comed, good for fresh systems
Steareth-2
Not decoded yet
C12-15 Alkyl Benzoate
C12-15 alkyl benzoate; emollient, emulsifier, and antistatic; aids stability and smoothness, moderate low comedogenicity.
Butyrospermum Parkii Butter
Shea butter for occlusive moisturizing; high melt point, rich texture, caution for oily skin.
Octyldodecanol
Light emollient/emulsifier at 1-5%; low comedogenic, non-greasy feel, broadly compatible, sensitive-skin friendly.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
High-molecular-weight thickener and emulsion stabilizer; requires electrolytes or acid adjustment near isoelectric point for optimal performance.
Isostearic Acid
Fatty acid derivative as emulsifier auxiliary and emollient; insoluble, requires homogenization, may feel slightly greasy
Cyclopentasiloxane
Cyclopentasiloxane for emollient/solvent; volatile silicone, smooth feel, check VOC regulations.
Acetyl Tyrosinamide
Not decoded yet
Saccharide Isomerate
Novel polyol humectant with skin feel improvement; high hydration, suitable for lightweight formulas.
Cyclohexasiloxane
Volatile cyclic silicone evaporating without residue; ensure compliance with EU limits on cyclic polydimethylsiloxanes, use octamer
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-1 for repair; requires lipid carrier, unstable in aqueous phase
Palmitoyl Tetrapeptide-7
Palmitoyl Tetrapeptide-7 boosts collagen; use 0.1–1%, formulate with lipid carriers
Vitis Vinifera Seed Extract
Grape seed extract with OPCs; potent antioxidant; used for skin protection and UV support; needs stabilizers.
Sodium PCA
Sodium PCA, NMF component, 1-10% humectant; salty/tacky at high levels.
Serine
Humectant amino acid, 1–3%; high water solubility, compatible with sensitive skin.
Glycine
Humectant amino acid, 1–3%; small molecule, low irritation.
Alanine
Amino acid for antistatic and conditioning; low irritation, slight salty taste at high levels
Lysine
Amino acid conditioner for anti-static hair care; low irritation at typical cosmetic concentrations.
Arginine
Arginine for moisturizing/conditioning; amino acid, high biocompatibility, often used in blends.
Threonine
Threonine, essential amino acid for hair/skin; blended with other AAs for balance.
Proline
Proline, amino-acid humectant; boosts stratum corneum hydration, stable at pH 4-5.
Cetyl Alcohol
Cetyl alcohol for emulsification/thickening; high concentration >10% may irritate.
Propylene Glycol
Polyol humectant at 3-10%; hygroscopic, slight tackiness, mild irritation at high conc., verify preservative efficacy, no allergen.
Betaine
Betaine for mild moisturizing/surfactant; low concentration 1-2% common, high may irritate.
Sorbitol
Polyol humectant with strong hygroscopy; tacky at high levels, pair with occlusives; also a solvent or adjuster.
Isopropyl Myristate
Light synthetic ester, fast-drying and non-greasy; high comedogenic risk, limit in acne-prone skin
Glutamic Acid
Glutamic acid, non-essential amino acid humectant; high levels can be astringent, buffer needed.
Butylene Glycol
Polyol humectant and solvent at 1–5%; aids solubilization, light feel
Polysorbate 60
Non-ionic emulsifier and solubilizer for O/W or W/O stability; may cause mild stinging on sensitive skin, typically 1-5%.
Sorbitan Isostearate
Non-ionic emulsifier (low HLB); typically used in blends, low comedogenicity, soft skin feel.
Carbomer
Gelling thickener requiring neutralization; watch out for ion compatibility
Polysorbate 20
Non-ionic emulsifier and cleansing surfactant; contains PEG, control microbial load.
Steareth-20
Not decoded yet
Ammonium Hydroxide
Strong alkaline pH adjuster; use in low concentrations to neutralize acids, avoid direct mixing with strong acids.
Disodium EDTA
Chelating agent at 0.05–0.5%; sequesters metal ions for stability, boosts preservative efficacy
Caprylyl Glycol
Polyol conditioner and preservative booster at 0.5–3%; emollient feel, often paired with 1,2-hexanediol
Sodium Bisulfite
Reducing agent and preservative in hair waving/straightening; irritating; restricted use
Xanthan Gum
Natural thickener at 0.1–1%; provides gel texture, pH-stable, requires full hydration
Phenoxyethanol
Broad-spectrum preservative at ≤1%; may irritate sensitive eye areas, often paired with ethylhexylglycerin
Chlorphenesin
Phenolic antimicrobial; strict EU limits apply, potential allergen, careful dosing required for leave-on products.
Methyldihydrojasmonate
Methyl dihydrojasmonate, jasmine accord; synthetic fragrance, potential allergen.
Isobutyl Methyl Tetrahydropyranol
Fragrance component providing specific scent, listed allergen, usage levels controlled
Ethylene Brassylate
Ethylene brassylate for fragrance and toning; potential sensitizer
Methyl Decenol
Aliphatic alcohol fragrance with fruity/fatty notes, perceivable at trace levels, low allergen risk
Ci 14700
Red azo dye restricted to hair dye products only; not for leave-on or general skin care
Ci 19140
Acid Yellow 23 lake; for coloring and hair dyeing. High water solubility and precipitation risk, pH control required.

Source: full ingredient list published on the product label, collected 2026-09-19. Ratings are our internal reading, not a regulatory conclusion. · Product page

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