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neutrogena Spot Controlling+ Daily Serum

neutrogena Neutrogena Spot Controlling+ Daily Serum lists 16 ingredients on its label, 16 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Aqua
  2. Propylene Glycol
  3. Glycolic Acid
  4. Dimethicone
  5. Sodium Hydroxide
  6. Mandelic Acid
  7. Gluconolactone
  8. Neopentyl Glycol Diheptanoate
  9. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  10. Salicylic Acid
  11. T-Butyl Alcohol
  12. Dimethicone Crosspolymer
  13. Polyacrylate Crosspolymer-6
  14. Polysorbate 60
  15. Sorbitan Isostearate
  16. Disodium EDTA

Highlights

Free of fragranceFree of parabensFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains siliconesContains alcoholContains PEG

Key ingredients

SOLVENT
Aqua
HUMECTANT
Propylene Glycol
BUFFERING
Glycolic AcidSodium Hydroxide
ANTIFOAMING
Dimethicone
ANTIMICROBIAL
Mandelic Acid
CHELATING
Gluconolactone
SKIN CONDITIONING - EMOLLIENT
Neopentyl Glycol Diheptanoate

Other ingredients

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerSalicylic AcidT-Butyl AlcoholDimethicone CrosspolymerPolyacrylate Crosspolymer-6Polysorbate 60Sorbitan IsostearateDisodium EDTA

Skim through

IngredientWhat it doesIrr. · Com.Rating
AquaSOLVENT0 · 0Green
Propylene GlycolHUMECTANT, FRAGRANCE, SOLVENT, VISCOSITY CONTROLLING, SKIN CONDITIONING - HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS1 · 0Green
Glycolic AcidBUFFERING2 · 0Green
DimethiconeANTIFOAMING, SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING, SKIN PROTECTING0 · 0Green
Sodium HydroxideBUFFERING, DENATURANT · 限制 III/15a3 · –Green
Mandelic AcidANTIMICROBIAL2 · 0Green
GluconolactoneCHELATING, SKIN CONDITIONING2 · 1Green
Neopentyl Glycol DiheptanoateSKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING0 · –Green
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerEMULSION STABILISING, VISCOSITY CONTROLLING0 · 0Green
Salicylic AcidANTI-SEBORRHEIC, HAIR CONDITIONING, KERATOLYTIC, FRAGRANCE, PRESERVATIVE, SKIN CONDITIONING · 限制 III/98 V/32 · 0Yellow
T-Butyl AlcoholDENATURANT, SOLVENT, PERFUMING2 · 0Green
Dimethicone CrosspolymerEMULSION STABILISING, HAIR FIXING, VISCOSITY CONTROLLING0 · 0Green
Polyacrylate Crosspolymer-6EMULSION STABILISING, VISCOSITY CONTROLLING0 · 0Green
Polysorbate 60SURFACTANT - EMULSIFYING, SURFACTANT - CLEANSING1 · –Green
Sorbitan IsostearateSURFACTANT - EMULSIFYING0 · 1Green
Disodium EDTACHELATING, VISCOSITY CONTROLLING0 · 0Green

Ingredients explained

Aqua
Solvent, main base; microbial control is critical
Propylene Glycol
Polyol humectant at 3-10%; hygroscopic, slight tackiness, mild irritation at high conc., verify preservative efficacy, no allergen.
Glycolic Acid
Glycolic acid for exfoliation; requires buffering at concentrations >10%, avoid combination with other acids.
Dimethicone
Silicone occlusive at 1–5%; provides smooth feel, non-penetrating, suitable for sensitive skin
Sodium Hydroxide
Strong base neutralizer for pH adjustment; handle with extreme care
Mandelic Acid
Alpha-hydroxy acid for exfoliation and antibacterial effects; mild penetration, less photosensitivity than other AHAs
Gluconolactone
Multifunctional agent for chelation and permeation; acidic, may irritate at high levels, buffer recommended.
Neopentyl Glycol Diheptanoate
Light emollient ester, non-greasy, improves product spreadability.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
High-molecular-weight thickener and emulsion stabilizer; requires electrolytes or acid adjustment near isoelectric point for optimal performance.
Salicylic Acid
Lipophilic BHA at 0.5-2%; exfoliant/sebum control, irritation/sensitization at high conc., photosensitivity (SPF needed), avoid sensitive/pregnant.
T-Butyl Alcohol
Fast-evaporating solvent; sharp odor and potential irritation at high levels, limit usage
Dimethicone Crosspolymer
Crosslinked silicone polymer providing silkiness and viscosity control; for hair and skin; inert but hard to biodegrade.
Polyacrylate Crosspolymer-6
Water-soluble thickener; requires neutralizer, performs best at pH 5–7
Polysorbate 60
Non-ionic emulsifier and solubilizer for O/W or W/O stability; may cause mild stinging on sensitive skin, typically 1-5%.
Sorbitan Isostearate
Non-ionic emulsifier (low HLB); typically used in blends, low comedogenicity, soft skin feel.
Disodium EDTA
Chelating agent at 0.05–0.5%; sequesters metal ions for stability, boosts preservative efficacy

Source: full ingredient list published on the product label, collected 2026-09-19. Ratings are our internal reading, not a regulatory conclusion. · Product page

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