METHYLISOTHIAZOLINONE
甲基异噻唑啉酮
Also known as 2-Methyl-2H-isothiazol-3-one
CAS 2682-20-4EC 220-239-6PubChem CID 39800
What it is and how it is used
Strong preservative; high allergy risk, EU restricted for leave-on products, high formulation risk
Status in national inventories
| China · Inventory of existing ingredients | 03333 | 按照《化妆品安全技术规范》要求使用 |
|---|---|---|
| China · STSC prohibited / restricted | CN-112/31 | 准用防腐剂(表4) · 序号 31 · 最大允许浓度 0.01% |
| EU · CosIng | 35341 | 功能 PRESERVATIVE · 限制 V/57 V/39 |
| Korea · Safety standards | KR-2/1063 | 附录 2 限用 · 防腐剂 · 限量 0.0015% in products that are washed off after use (However, do not use in combination with the mixture of methylchloroisothiazolinone and methylisothiazolinone.) · Do not use in other products |
| Brazil · ANVISA | BR-528/57 | 准用防腐剂 · RDC 528/2021 第 57 项 · 最大浓度 0,0015% em produtos que se enxáguem. · -Proibido em produtos que não se enxáguem (incluindo os lenços umedecidos). -A utilização da mistura de methylchloroisothiazolinone e methyl |
Matched on the exact INCI name; salts, esters and synonyms may be missed. The latest official text prevails.
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Functions from EU CosIng and the China inventory; irritancy, comedogenicity and rating are our internal reading, not a regulatory conclusion. Structure and molecular data from PubChem.
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