madeca-derma Madeca Derma Microbiome Ampoule

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

1. Water
2. Diphenyl Dimethicone
3. Pentylene Glycol
4. Niacinamide
5. Epidermidibacterium Keratini Ferment Filtrate
6. Sodium Hyaluronate
7. Fructooligosaccharides
8. Fructose
9. Dextrin
10. Mannose
11. Ribose
12. Hedera Helix Extract
13. Collagen
14. Hydrolyzed Collagen
15. Acetyl Dipeptide-1 Cetyl Ester
16. Palmitoyl Tripeptide-5
17. Acetyl Hexapeptide-8
18. Nonapeptide-1
19. Hexapeptide-9
20. Glycerin
21. Methylpropanediol
22. Sodium PCA
23. Butylene Glycol
24. Eclipta Prostrata Extract
25. Panthenol
26. Beta-Glucan
27. Sodium Citrate
28. Melia Azadirachta Leaf Extract
29. Chlorella Vulgaris Extract
30. Citric Acid
31. Glucose
32. Glycine Soja Seed Extract
33. Curcuma Longa Root Extract
34. Hippophae Rhamnoides Oil
35. Moringa Oleifera Seed Oil
36. 1,2-Hexanediol
37. Melia Azadirachta Flower Extract
38. Octanediol
39. Ethylhexylglycerin
40. Adenosine
41. Corallina Officinalis Extract
42. Melia Azadirachta Bark Extract
43. Ocimum Sanctum Leaf Extract
44. Sorbitan Laurate
45. Hydroxyethylcellulose
46. Caprylyl Glycol
47. Calcium Chloride
48. Magnesium Sulfate
49. Fragrance

Highlights

Free of parabensFree of sulfatesFree of mineral oilFree of formaldehyde releasersContains siliconesContains animal-derivedContains alcoholContains fragranceContains essential oilsContains EU-26 allergens

Key ingredients

ANTIPLAQUE

Water

ANTIFOAMING

Diphenyl Dimethicone

SKIN CONDITIONING

Pentylene Glycol

SMOOTHING

Niacinamide

SKIN CONDITIONING - EMOLLIENT

Epidermidibacterium Keratini Ferment Filtrate

HUMECTANT

Sodium HyaluronateFructooligosaccharidesFructose

Other ingredients

DextrinMannoseRiboseHedera Helix ExtractCollagenHydrolyzed CollagenAcetyl Dipeptide-1 Cetyl EsterPalmitoyl Tripeptide-5Acetyl Hexapeptide-8Nonapeptide-1Hexapeptide-9GlycerinMethylpropanediolSodium PCAButylene GlycolEclipta Prostrata ExtractPanthenolBeta-GlucanSodium CitrateMelia Azadirachta Leaf ExtractChlorella Vulgaris ExtractCitric AcidGlucoseGlycine Soja Seed ExtractCurcuma Longa Root ExtractHippophae Rhamnoides OilMoringa Oleifera Seed Oil1,2-HexanediolMelia Azadirachta Flower ExtractOctanediolEthylhexylglycerinAdenosineCorallina Officinalis ExtractMelia Azadirachta Bark ExtractOcimum Sanctum Leaf ExtractSorbitan LaurateHydroxyethylcelluloseCaprylyl GlycolCalcium ChlorideMagnesium SulfateFragrance

Skim through

Ingredients explained

Water

Primary solvent and base; requires preservative system to prevent microbial growth

Diphenyl Dimethicone

Silicone for emollience and antistatic; used in hair and skin care, check compatibility with other silicones

Pentylene Glycol

Polyol humectant at 1-3%; low irritancy, suitable for sensitive skin

Niacinamide

Niacinamide at 2–5%; improves texture, controls oil, brightens; high levels may cause sensitivity

Epidermidibacterium Keratini Ferment Filtrate

Probiotic ferment filtrate for skin conditioning; typically used at low levels

Sodium Hyaluronate

Potent humectant at 0.1–2%; different MW for penetration depth, high levels may draw moisture

Fructooligosaccharides

Prebiotic polysaccharide for hydration/skin conditioning; high levels may feel sticky

Fructose

Strong humectant; high levels can increase viscosity and hygroscopicity.

Dextrin

Polymer thickener and binder from starch fermentation; biodegradable, hygroscopic, may affect powder flow

Mannose

Monosaccharide humectant that binds glycosaminoglycans to enhance hydration; extremely low allergenicity

Ribose

Ribose, humectant and skin conditioner; small molecule with high hygroscopicity, blend with other humectants.

Hedera Helix Extract

Plant polyphenol conditioner, soothing and astringent; safe for sensitive skin

Collagen

Hydrating conditioning agent; soluble protein used in hair care and toners; forms occlusive layer.

Hydrolyzed Collagen

Hydrolyzed protein for film-forming and moisture; molecular weight limits penetration, check source for shellfish allergies

Acetyl Dipeptide-1 Cetyl Ester

Acetyl dipeptide-1 cetyl ester for hair and skin; ester structure, avoid for oily skin, check compatibility.

Palmitoyl Tripeptide-5

Peptide actives for skin conditioning; typically used at low levels.

Acetyl Hexapeptide-8

Acetyl hexapeptide-8; signal peptide, low concentration, used for firming and hydration, low irritancy.

Nonapeptide-1

Nonapeptide-1 for hair/skin conditioning; enhances shine and strength, low irritation.

Hexapeptide-9

Hexapeptide-9 (Acetyl Hexapeptide); signal peptide for fibroblast stimulation, typically used at 0.5-1%.

Glycerin

Workhorse humectant at 3–10%; tacky at high levels, pair with occlusives

Methylpropanediol

Diol solvent and extraction carrier; enhances solubility of actives, low irritation profile.

Sodium PCA

Sodium PCA, NMF component, 1-10% humectant; salty/tacky at high levels.

Butylene Glycol

Polyol humectant and solvent at 1–5%; aids solubilization, light feel

Eclipta Prostrata Extract

Eclipta prostrata extract used for antioxidant and hair coloring; water-soluble, low irritation and comedogenic risk at typical levels.

Panthenol

Panthenol (vitamin B5) at 1–5%; moisturizing and reparative, supports barrier recovery

Beta-Glucan

Polysaccharide for soothing and hydration; high MW acts on the surface, poor penetration into deep dermis.

Sodium Citrate

Sodium citrate for buffering and chelating; adjust pH, careful with strong acid reactions.

Melia Azadirachta Leaf Extract

Plant extract, 0.1–1%; has antibacterial properties, allergy testing advised.

Chlorella Vulgaris Extract

Algae extract for skin conditioning and antioxidant; typically 1-5%, monitor stability

Citric Acid

Buffer and chelator at 0.1–2%; adjusts pH, may irritate sensitive skin at low pH

Glucose

Low-MW humectant and buffer; high hygroscopicity requires careful preservation and humidity control.

Glycine Soja Seed Extract

Soybean extract for skin conditioning; low allergen risk, monitor batch protein variability.

Curcuma Longa Root Extract

Turmeric root extract, contains curcumin, colorant/antioxidant; high doses may sensitize.

Hippophae Rhamnoides Oil

Sea buckthorn oil rich in carotenoids; viscous and may stain light formulations.

Moringa Oleifera Seed Oil

Light emollient oil rich in oleic acid; moderate comedogenic risk.

1,2-Hexanediol

Polyol solvent and preservative booster at 1–5%; light feel, can replace some traditional preservatives

Melia Azadirachta Flower Extract

Plant extract, 0.1–1%; antioxidant properties, light sensitivity advised.

Octanediol

Octanediol serves as a plasticizer and preservative booster; safe at low concentrations, often used in blends.

Ethylhexylglycerin

Mild conditioner and preservative booster at 0.5–1%; reduces preservative load, smooth feel

Adenosine

Skin conditioner at 0.1-1%; used for anti-aging and repair

Corallina Officinalis Extract

Corallina extract, polysaccharide-rich humectant/film former; algal source, batch variation.

Melia Azadirachta Bark Extract

Antibacterial and skin-protecting; active components may cause sensitization

Ocimum Sanctum Leaf Extract

Holy basil leaf extract for conditioning; complex botanical, patch test recommended for compatibility

Sorbitan Laurate

O/W emulsifier; low-comedogenic ester, verify emulsion stability.

Hydroxyethylcellulose

Water-soluble cellulose ether for thickening and suspension stabilization; sensitive to ions, electrolytes reduce viscosity, use at pH 7-8.

Caprylyl Glycol

Polyol conditioner and preservative booster at 0.5–3%; emollient feel, often paired with 1,2-hexanediol

Calcium Chloride

Cross-linker and viscosity controller for gels; astringent at high levels, check skin tolerance

Magnesium Sulfate

Bulk agent at 0.1–1%; highly water-soluble, avoid high local concentration.

Fragrance

Fragrance; concentration must control allergen risk, label specific components

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