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medicube Zero Pore One-day Serum

medicube Medicube Zero Pore One-day Serum lists 42 ingredients on its label, 37 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Water
  2. Gluconolactone
  3. Methylpropanediol
  4. Glycerin
  5. Propanediol
  6. Tromethamine
  7. Polyglycerin-3
  8. Niacinamide
  9. 1,2-Hexanediol
  10. Citric Acid
  11. Dimethicone
  12. Butylene Glycol
  13. C12-14 Pareth-12
  14. Hydroxyethylcellulose
  15. Salicylic Acid
  16. Ammonium Acryloyldimethyltaurate/VP Copolymer
  17. Sodium Polyacryloyldimethyl Taurate
  18. Lecithin
  19. Allantoin
  20. Lactic Acid
  21. Glycolic Acid
  22. Ethylhexylglycerin
  23. Adenosine
  24. Dextrin
  25. Indigofera Tinctoria Extract
  26. Sodium Hyaluronate
  27. Hyaluronic Acid
  28. Sodium Citrate
  29. Hemerocallis Fulva Flower Extract
  30. Gardenia Florida Fruit Extract
  31. Hydrolyzed Hyaluronic Acid
  32. Hydrolyzed Sodium Hyaluronate
  33. Sodium Hyaluronate Crosspolymer
  34. Trisodium Phosphate
  35. Myosotis Sylvatica Flower/Leaf/Stem Extract
  36. Pentylene Glycol
  37. Hydroxypropyltrimonium Hyaluronate
  38. Sodium Acetylated Hyaluronate
  39. Centella Asiatica Extract
  40. Madecassoside
  41. Lactobacillus Ferment Lysate
  42. Taraxacum Officinale Leaf Extract

Highlights

Free of fragranceFree of parabensFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains alcoholContains silicones

Formulation view Water-based serum with polyols. Gluconolactone, salicylic, and fruit acids exfoliate; niacinamide and hyaluronic acids repair. Centella and allantoin soothe. Ideal for oily, combination skin pore care. Formulator's note: Strong acidic system buffered by humectants; silicone adds slip. Suitable for seeking instant clarity, requiring tolerance building.

Key ingredients

ANTIPLAQUE
Water
CHELATING
Gluconolactone
SOLVENT
MethylpropanediolPropanediol
DENATURANT
Glycerin
BUFFERING
Tromethamine
SMOOTHING
Niacinamide
SKIN CONDITIONING
1,2-Hexanediol

Other ingredients

Polyglycerin-3Citric AcidDimethiconeButylene GlycolC12-14 Pareth-12HydroxyethylcelluloseSalicylic AcidAmmonium Acryloyldimethyltaurate/VP CopolymerSodium Polyacryloyldimethyl TaurateLecithinAllantoinLactic AcidGlycolic AcidEthylhexylglycerinAdenosineDextrinIndigofera Tinctoria ExtractSodium HyaluronateHyaluronic AcidSodium CitrateHemerocallis Fulva Flower ExtractGardenia Florida Fruit ExtractHydrolyzed Hyaluronic AcidHydrolyzed Sodium HyaluronateSodium Hyaluronate CrosspolymerTrisodium PhosphateMyosotis Sylvatica Flower/Leaf/Stem ExtractPentylene GlycolHydroxypropyltrimonium HyaluronateSodium Acetylated HyaluronateCentella Asiatica ExtractMadecassosideLactobacillus Ferment LysateTaraxacum Officinale Leaf Extract

Skim through

IngredientWhat it doesIrr. · Com.Rating
WaterANTIPLAQUE, SKIN CONDITIONING, SOLVENT0 · 0Green
GluconolactoneCHELATING, SKIN CONDITIONING2 · 1Green
MethylpropanediolSOLVENT0 · 0Green
GlycerinDENATURANT, HAIR CONDITIONING, HUMECTANT, ORAL CARE, SKIN PROTECTING, SOLVENT, VISCOSITY CONTROLLING, PERFUMING, FRAGRANCE, SKIN CONDITIONING - HUMECTANT0 · 0Green
PropanediolSOLVENT, VISCOSITY CONTROLLING0 · 0Green
TromethamineBUFFERING, FRAGRANCE · 限制 III/610 · –Green
Polyglycerin-3Not decoded yet
NiacinamideSMOOTHING0 · 0Green
1,2-HexanediolSKIN CONDITIONING, SOLVENT0 · 0Green
Citric AcidBUFFERING, CHELATING, FRAGRANCE1 · 0Green
DimethiconeANTIFOAMING, SKIN CONDITIONING - EMOLLIENT, SKIN CONDITIONING, SKIN PROTECTING0 · 0Green
Butylene GlycolHUMECTANT, FRAGRANCE, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING0 · 0Green
C12-14 Pareth-12Not decoded yet
HydroxyethylcelluloseBINDING, EMULSION STABILISING, FILM FORMING, LIGHT STABILIZER, VISCOSITY CONTROLLING0 · 0Green
Salicylic AcidANTI-SEBORRHEIC, HAIR CONDITIONING, KERATOLYTIC, FRAGRANCE, PRESERVATIVE, SKIN CONDITIONING · 限制 III/98 V/32 · 0Yellow
Ammonium Acryloyldimethyltaurate/VP CopolymerVISCOSITY CONTROLLING0 · 0Green
Sodium Polyacryloyldimethyl TaurateEMULSION STABILISING, VISCOSITY CONTROLLING0 · 0Green
LecithinANTISTATIC, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING, SKIN CONDITIONING0 · 0Green
AllantoinSKIN CONDITIONING, SKIN PROTECTING, SOOTHING0 · 0Green
Lactic AcidBUFFERING, HUMECTANT, SKIN CONDITIONING1 · 0Green
Glycolic AcidBUFFERING2 · 0Green
EthylhexylglycerinDEODORANT, SKIN CONDITIONING0 · 0Green
AdenosineSKIN CONDITIONING0 · 0Green
DextrinABSORBENT, BINDING, BULKING, VISCOSITY CONTROLLING0 · 0Green
Indigofera Tinctoria ExtractNot decoded yet
Sodium HyaluronateHUMECTANT, SKIN CONDITIONING0 · 0Green
Hyaluronic AcidANTISTATIC, HUMECTANT, MOISTURISING, SKIN CONDITIONING0 · 0Green
Sodium CitrateBUFFERING, CHELATING, FRAGRANCE0 · 0Green
Hemerocallis Fulva Flower ExtractNot decoded yet
Gardenia Florida Fruit ExtractCOLORANT, SKIN CONDITIONING - MISCELLANEOUS0 · 0Green
Hydrolyzed Hyaluronic AcidHAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING0 · 0Green
Hydrolyzed Sodium HyaluronateSKIN CONDITIONING0 · 0Green
Sodium Hyaluronate CrosspolymerHUMECTANT, SKIN CONDITIONING0 · 0Green
Trisodium PhosphateBUFFERING, CHELATING2 · 0Green
Myosotis Sylvatica Flower/Leaf/Stem ExtractNot decoded yet
Pentylene GlycolSKIN CONDITIONING, SOLVENT0 · 0Green
Hydroxypropyltrimonium HyaluronateFILM FORMING0 · 0Green
Sodium Acetylated HyaluronateHUMECTANT0 · 0Green
Centella Asiatica ExtractCLEANSING, SKIN CONDITIONING, SMOOTHING, SOOTHING, TONIC0 · 0Green
MadecassosideANTIOXIDANT, SKIN CONDITIONING0 · 0Green
Lactobacillus Ferment LysateSKIN CONDITIONING0 · 0Green
Taraxacum Officinale Leaf ExtractSKIN CONDITIONING0 · –Green

Ingredients explained

Water
Primary solvent and base; requires preservative system to prevent microbial growth
Gluconolactone
Multifunctional agent for chelation and permeation; acidic, may irritate at high levels, buffer recommended.
Methylpropanediol
Diol solvent and extraction carrier; enhances solubility of actives, low irritation profile.
Glycerin
Workhorse humectant at 3–10%; tacky at high levels, pair with occlusives
Propanediol
Polyol solvent at 1–5%; light feel, aids solubilization, propylene glycol alternative
Tromethamine
pH adjuster, alkaline; precise dosing required
Polyglycerin-3
Not decoded yet
Niacinamide
Niacinamide at 2–5%; improves texture, controls oil, brightens; high levels may cause sensitivity
1,2-Hexanediol
Polyol solvent and preservative booster at 1–5%; light feel, can replace some traditional preservatives
Citric Acid
Buffer and chelator at 0.1–2%; adjusts pH, may irritate sensitive skin at low pH
Dimethicone
Silicone occlusive at 1–5%; provides smooth feel, non-penetrating, suitable for sensitive skin
Butylene Glycol
Polyol humectant and solvent at 1–5%; aids solubilization, light feel
C12-14 Pareth-12
Not decoded yet
Hydroxyethylcellulose
Water-soluble cellulose ether for thickening and suspension stabilization; sensitive to ions, electrolytes reduce viscosity, use at pH 7-8.
Salicylic Acid
Lipophilic BHA at 0.5-2%; exfoliant/sebum control, irritation/sensitization at high conc., photosensitivity (SPF needed), avoid sensitive/pregnant.
Ammonium Acryloyldimethyltaurate/VP Copolymer
Cationic polymer providing suspension, thickening, and conditioning; often paired with anionic thickening systems, low usage, imparts slip.
Sodium Polyacryloyldimethyl Taurate
Sodium polyacryloyldimethyl taurate for emulsion stabilization and thickening; ionic polymer, check ion compatibility.
Lecithin
Phospholipid emulsifier at 1-5%; biocompatible, moisturizing/antioxidant, prone to oxidation (add TBHQ), mild for sensitive skin.
Allantoin
Skin soother at 0.5-2%; promotes cell regeneration
Lactic Acid
AHA pH adjuster at 0.5-5%; exfoliation/humectancy, mild at low conc., irritating at high, avoid conflict with alkaline preservatives.
Glycolic Acid
Glycolic acid for exfoliation; requires buffering at concentrations >10%, avoid combination with other acids.
Ethylhexylglycerin
Mild conditioner and preservative booster at 0.5–1%; reduces preservative load, smooth feel
Adenosine
Skin conditioner at 0.1-1%; used for anti-aging and repair
Dextrin
Polymer thickener and binder from starch fermentation; biodegradable, hygroscopic, may affect powder flow
Indigofera Tinctoria Extract
Not decoded yet
Sodium Hyaluronate
Potent humectant at 0.1–2%; different MW for penetration depth, high levels may draw moisture
Hyaluronic Acid
High-water-binding humectant at 0.1-1%; high-MW for surface film, low-MW for dermal potential, check cationic compatibility.
Sodium Citrate
Sodium citrate for buffering and chelating; adjust pH, careful with strong acid reactions.
Hemerocallis Fulva Flower Extract
Not decoded yet
Gardenia Florida Fruit Extract
Extract for color and conditioning; watch dark batches in clear systems
Hydrolyzed Hyaluronic Acid
Low-MW humectant with superior penetration vs high-MW; 0.1-0.5% typical, hygroscopic, store dry to prevent clumping.
Hydrolyzed Sodium Hyaluronate
Low-molecular-weight hyaluronic acid derivative with better penetration and strong hydration; different molecular weights provide hydration at various depths, typical concentration 0.1-1%.
Sodium Hyaluronate Crosspolymer
Crosslinked high-MW HA; forms surface hydrogel for long-lasting hydration, minimal penetration, physical film-forming.
Trisodium Phosphate
Strong alkaline buffer for high pH regulation; use precise dosing to avoid irritation
Myosotis Sylvatica Flower/Leaf/Stem Extract
Not decoded yet
Pentylene Glycol
Polyol humectant at 1-3%; low irritancy, suitable for sensitive skin
Hydroxypropyltrimonium Hyaluronate
Cationic hyaluronic acid, 0.1–1%; water-soluble thickener and conditioning agent.
Sodium Acetylated Hyaluronate
Acetylated HA; modified for hydrophobicity, improved penetration and non-tacky feel compared to standard HA.
Centella Asiatica Extract
Centella asiatica extract for soothing/repair; low irritation, common in sensitive skin products.
Madecassoside
Triterpenoid glycoside with soothing, repairing, and antioxidant effects; typical concentration 0.1-1%, suitable for sensitive or compromised skin, good stability.
Lactobacillus Ferment Lysate
Lactobacillus ferment lysate for skin conditioning; provides soothing and hydration, low sensitization risk if sterile.
Taraxacum Officinale Leaf Extract
Taraxacum leaf extract for soothing; plant extract may contain particulates, filtration needed.

Source: full ingredient list published on the product label, collected 2026-09-20. Ratings are our internal reading, not a regulatory conclusion. · Product page

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