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natinuel Defend C25

natinuel Natinuel Defend C25 lists 18 ingredients on its label, 17 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Aqua
  2. Methylpropanediol
  3. Sodium Hyaluronate
  4. Glycerin
  5. Milk Thistle Fruit Extract
  6. Ascorbyl Methylsilanol Pectinate
  7. Lecithin
  8. Carnosine
  9. Melatonin
  10. Cyclodextrin
  11. Thioctic Acid
  12. Alcohol
  13. Tocopherol
  14. Sodium Hydroxide
  15. Disodium EDTA
  16. Phenoxyethanol
  17. Ethylhexylglycerin
  18. Ascorbic Acid

Highlights

Free of fragranceFree of parabensFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains alcoholContains silicones

Key ingredients

SOLVENT
AquaMethylpropanediol
HUMECTANT
Sodium Hyaluronate
DENATURANT
Glycerin
ANTIOXIDANT
Ascorbyl Methylsilanol PectinateMelatonin
ANTISTATIC
Lecithin
SKIN CONDITIONING
Carnosine

Other ingredients

Milk Thistle Fruit ExtractCyclodextrinThioctic AcidAlcoholTocopherolSodium HydroxideDisodium EDTAPhenoxyethanolEthylhexylglycerinAscorbic Acid

Skim through

IngredientWhat it doesIrr. · Com.Rating
AquaSOLVENT0 · 0Green
MethylpropanediolSOLVENT0 · 0Green
Sodium HyaluronateHUMECTANT, SKIN CONDITIONING0 · 0Green
GlycerinDENATURANT, HAIR CONDITIONING, HUMECTANT, ORAL CARE, SKIN PROTECTING, SOLVENT, VISCOSITY CONTROLLING, PERFUMING, FRAGRANCE, SKIN CONDITIONING - HUMECTANT0 · 0Green
Milk Thistle Fruit ExtractNot decoded yet
Ascorbyl Methylsilanol PectinateANTIOXIDANT, VISCOSITY CONTROLLING0 · 0Green
LecithinANTISTATIC, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING, SKIN CONDITIONING0 · 0Green
CarnosineSKIN CONDITIONING0 · –Green
MelatoninANTIOXIDANT0 · 0Green
CyclodextrinABSORBENT, CHELATING0 · 0Green
Thioctic AcidANTIOXIDANTGreen
AlcoholANTIFOAMING, ANTIMICROBIAL, ASTRINGENT, FRAGRANCE, SOLVENT, VISCOSITY CONTROLLING1 · 0Yellow
TocopherolANTIOXIDANT, FRAGRANCE, SKIN CONDITIONING - MISCELLANEOUS, SKIN CONDITIONING - OCCLUSIVE0 · 0Green
Sodium HydroxideBUFFERING, DENATURANT · 限制 III/15a3 · –Green
Disodium EDTACHELATING, VISCOSITY CONTROLLING0 · 0Green
PhenoxyethanolANTIMICROBIAL, PRESERVATIVE · 限制 V/291 · 0Yellow
EthylhexylglycerinDEODORANT, SKIN CONDITIONING0 · 0Green
Ascorbic AcidANTIOXIDANT, BUFFERING, FRAGRANCE, SKIN CONDITIONING2 · 0Green

Ingredients explained

Aqua
Solvent, main base; microbial control is critical
Methylpropanediol
Diol solvent and extraction carrier; enhances solubility of actives, low irritation profile.
Sodium Hyaluronate
Potent humectant at 0.1–2%; different MW for penetration depth, high levels may draw moisture
Glycerin
Workhorse humectant at 3–10%; tacky at high levels, pair with occlusives
Milk Thistle Fruit Extract
Not decoded yet
Ascorbyl Methylsilanol Pectinate
Silicon-based Vitamin C derivative for antioxidant activity and viscosity control; superior stability compared to traditional Vitamin C, suitable for formulation.
Lecithin
Phospholipid emulsifier at 1-5%; biocompatible, moisturizing/antioxidant, prone to oxidation (add TBHQ), mild for sensitive skin.
Carnosine
Dipeptide skin conditioner with antioxidant and buffering properties; used in synergy with other actives.
Melatonin
Melatonin, antioxidant; verify topical stability
Cyclodextrin
Cyclodextrin; used as a stabilizer or solubilizer to improve solubility of active ingredients and fragrances
Thioctic Acid
Alpha-lipoic acid; potent antioxidant; poor water solubility, often used as ester derivatives
Alcohol
Ethanol for solubility/drying at 5-15%; high conc. is drying/irritating, avoid lip/eye, low residue, balance with humectants.
Tocopherol
Natural antioxidant (vitamin E) at 0.1–1%; prone to oxidation, store protected from light
Sodium Hydroxide
Strong base neutralizer for pH adjustment; handle with extreme care
Disodium EDTA
Chelating agent at 0.05–0.5%; sequesters metal ions for stability, boosts preservative efficacy
Phenoxyethanol
Broad-spectrum preservative at ≤1%; may irritate sensitive eye areas, often paired with ethylhexylglycerin
Ethylhexylglycerin
Mild conditioner and preservative booster at 0.5–1%; reduces preservative load, smooth feel
Ascorbic Acid
Vitamin C, potent antioxidant requiring acidic environment for stability; oxidizes and discolors easily, needs light and air protection, concentration 1-10%, pure L-ascorbic acid is more irritating.

Source: full ingredient list published on the product label, collected 2026-09-19. Ratings are our internal reading, not a regulatory conclusion. · Product page

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