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isispharma Metroruboril A.Z.

isispharma Isispharma Metroruboril A.Z. lists 28 ingredients on its label, 28 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Aqua
  2. Azelaic Acid
  3. Betaine
  4. Caprylic/Capric Triglyceride
  5. Glycerin
  6. Butylene Glycol
  7. Pentylene Glycol
  8. Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
  9. Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
  10. Lauryl Glucoside
  11. Polyglyceryl-2 Dipolyhydroxystearate
  12. Glycyrrhetinic Acid
  13. Niacinamide
  14. Ethylhexylglycerin
  15. Panthenol
  16. Sclerotium Gum
  17. Chlorphenesin
  18. Escin
  19. O-Cymen-5-Ol
  20. Polysorbate 60
  21. Sorbitan Isostearate
  22. Ruscus Aculeatus Root Extract
  23. Ammonium Glycyrrhizate
  24. Citric Acid
  25. Centella Asiatica Leaf Extract
  26. Hydrolyzed Yeast Protein
  27. Calendula Officinalis Flower Extract
  28. Sodium Citrate

Highlights

Free of alcoholFree of fragranceFree of parabensFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains siliconesContains PEG

Key ingredients

SOLVENT
Aqua
BUFFERING
Azelaic Acid
HAIR CONDITIONING
Betaine
FRAGRANCE
Caprylic/Capric Triglyceride
DENATURANT
Glycerin
HUMECTANT
Butylene Glycol
SKIN CONDITIONING
Pentylene Glycol
VISCOSITY CONTROLLING
Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer

Other ingredients

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerLauryl GlucosidePolyglyceryl-2 DipolyhydroxystearateGlycyrrhetinic AcidNiacinamideEthylhexylglycerinPanthenolSclerotium GumChlorphenesinEscinO-Cymen-5-OlPolysorbate 60Sorbitan IsostearateRuscus Aculeatus Root ExtractAmmonium GlycyrrhizateCitric AcidCentella Asiatica Leaf ExtractHydrolyzed Yeast ProteinCalendula Officinalis Flower ExtractSodium Citrate

Skim through

IngredientWhat it doesIrr. · Com.Rating
AquaSOLVENT0 · 0Green
Azelaic AcidBUFFERING, FRAGRANCE3 · 0Green
BetaineHAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING - HUMECTANT0 · 0Green
Caprylic/Capric TriglycerideFRAGRANCE, SOLVENT, PERFUMING, SKIN CONDITIONING - OCCLUSIVE0 · 0Green
GlycerinDENATURANT, HAIR CONDITIONING, HUMECTANT, ORAL CARE, SKIN PROTECTING, SOLVENT, VISCOSITY CONTROLLING, PERFUMING, FRAGRANCE, SKIN CONDITIONING - HUMECTANT0 · 0Green
Butylene GlycolHUMECTANT, FRAGRANCE, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING0 · 0Green
Pentylene GlycolSKIN CONDITIONING, SOLVENT0 · 0Green
Vinyl Dimethicone/Methicone Silsesquioxane CrosspolymerVISCOSITY CONTROLLING0 · 0Green
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerEMULSION STABILISING, VISCOSITY CONTROLLING0 · 0Green
Lauryl GlucosideCLEANSING, SURFACTANT - CLEANSING0 · –Green
Polyglyceryl-2 DipolyhydroxystearateSKIN CONDITIONING0 · 1Green
Glycyrrhetinic AcidSKIN CONDITIONING0 · 0Green
NiacinamideSMOOTHING0 · 0Green
EthylhexylglycerinDEODORANT, SKIN CONDITIONING0 · 0Green
PanthenolANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING0 · 0Green
Sclerotium GumEMULSION STABILISING, SKIN CONDITIONING, VISCOSITY CONTROLLING0 · 0Green
ChlorphenesinANTIMICROBIAL, PRESERVATIVE · 限制 V/501 · 0Yellow
EscinTONIC1 · 0Green
O-Cymen-5-OlANTIMICROBIAL, DEODORANT, PRESERVATIVE · 限制 V/381 · 0Yellow
Polysorbate 60SURFACTANT - EMULSIFYING, SURFACTANT - CLEANSING1 · –Green
Sorbitan IsostearateSURFACTANT - EMULSIFYING0 · 1Green
Ruscus Aculeatus Root ExtractASTRINGENT, REFRESHING, SKIN CONDITIONING, SOOTHING, LIGHT STABILIZER, TONIC0 · –Green
Ammonium GlycyrrhizateFRAGRANCE, FLAVOURING, SKIN CONDITIONING - MISCELLANEOUS0 · 0Green
Citric AcidBUFFERING, CHELATING, FRAGRANCE1 · 0Green
Centella Asiatica Leaf ExtractSKIN CONDITIONING0 · –Green
Hydrolyzed Yeast ProteinANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING0 · 0Green
Calendula Officinalis Flower ExtractFRAGRANCE, SKIN CONDITIONING, PERFUMING0 · 0Green
Sodium CitrateBUFFERING, CHELATING, FRAGRANCE0 · 0Green

Ingredients explained

Aqua
Solvent, main base; microbial control is critical
Azelaic Acid
Acne and pigment agent; 15-20% can be irritating, needs controlled release or lower doses.
Betaine
Betaine for mild moisturizing/surfactant; low concentration 1-2% common, high may irritate.
Caprylic/Capric Triglyceride
Light occlusive and solvent at 1–10%; non-greasy feel, suitable for oily and combination skin
Glycerin
Workhorse humectant at 3–10%; tacky at high levels, pair with occlusives
Butylene Glycol
Polyol humectant and solvent at 1–5%; aids solubilization, light feel
Pentylene Glycol
Polyol humectant at 1-3%; low irritancy, suitable for sensitive skin
Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Rheology-modifying silicone polymer for suspension and feel; requires silicone-compatible system
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
High-molecular-weight thickener and emulsion stabilizer; requires electrolytes or acid adjustment near isoelectric point for optimal performance.
Lauryl Glucoside
Mild nonionic surfactant for cleansing; 1-5%, suitable for sensitive skin
Polyglyceryl-2 Dipolyhydroxystearate
Plant-derived emulsifier, mild feel; for O/W systems, combine with co-emulsifiers
Glycyrrhetinic Acid
Glycyrrhizic acid; anti-inflammatory; poor water solubility, needs solubilization.
Niacinamide
Niacinamide at 2–5%; improves texture, controls oil, brightens; high levels may cause sensitivity
Ethylhexylglycerin
Mild conditioner and preservative booster at 0.5–1%; reduces preservative load, smooth feel
Panthenol
Panthenol (vitamin B5) at 1–5%; moisturizing and reparative, supports barrier recovery
Sclerotium Gum
Non-ionic gum for gels; neutral pH, requires dissolution via heating or fine milling
Chlorphenesin
Phenolic antimicrobial; strict EU limits apply, potential allergen, careful dosing required for leave-on products.
Escin
Horse chestnut extract for venous circulation and anti-inflammatory; caution near eyes; potential plant-based allergen
O-Cymen-5-Ol
Antioxidant and antimicrobial; low levels for preservation; irritating at high concentrations, restricted use.
Polysorbate 60
Non-ionic emulsifier and solubilizer for O/W or W/O stability; may cause mild stinging on sensitive skin, typically 1-5%.
Sorbitan Isostearate
Non-ionic emulsifier (low HLB); typically used in blends, low comedogenicity, soft skin feel.
Ruscus Aculeatus Root Extract
Plant extract with polysaccharides and flavonoids; for firming and anti-irritation, < 1%.
Ammonium Glycyrrhizate
Soothing anti-inflammatory and emulsifier; derived from licorice, minor allergen risk
Citric Acid
Buffer and chelator at 0.1–2%; adjusts pH, may irritate sensitive skin at low pH
Centella Asiatica Leaf Extract
Centella asiatica extract for repair and soothing; contains asiaticoside, good for barrier
Hydrolyzed Yeast Protein
Hydrolyzed protein for moisture, anti-static, and barrier repair.
Calendula Officinalis Flower Extract
Calendula extract for soothing and repair; aqueous systems, monitor extract residues.
Sodium Citrate
Sodium citrate for buffering and chelating; adjust pH, careful with strong acid reactions.

Source: full ingredient list published on the product label, collected 2026-09-19. Ratings are our internal reading, not a regulatory conclusion. · Product page

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