Cetaphil advanced daily defence serum
Cetaphil cetaphil advanced daily defence serum lists 16 ingredients on its label, 16 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.
Ingredients overview
Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.
Ingredients are listed in label order; the order reflects the label only, not exact concentrations.
Highlights
Free of alcoholFree of fragranceFree of parabensFree of siliconesFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains PEG
Formulation view Water-based serum. Polyol solvent system for actives. Niacinamide for clarity, EGCG and hyaluronic acids for moisture, allantoin and tocopherol for soothing. Oil-free, lightweight texture. Suited for combination or oily skin. Factory note: Preservative-free system relies on polyols and chelants; strict microbial control is essential.
Key ingredients
- ANTIPLAQUE
- Water
- HUMECTANT
- Butylene Glycol
- SURFACTANT - EMULSIFYING
- PEG/PPG-8/3 LauratePolyglyceryl-4 Caprate
- SKIN CONDITIONING
- Pentylene Glycol1,2-Hexanediol
- SMOOTHING
- Niacinamide
- ANTIOXIDANT
- Epigallocatechin Gallatyl Glucoside
Other ingredients
Hydrolyzed Hyaluronic AcidAllantoinTocopheryl AcetateAmmonium Acryloyldimethyltaurate/VP CopolymerSodium HyaluronateTocopherolSodium GluconateCitric Acid
Skim through
| Ingredient | What it does | Irr. · Com. | Rating |
|---|---|---|---|
| Water | ANTIPLAQUE, SKIN CONDITIONING, SOLVENT | 0 · 0 | Green |
| Butylene Glycol | HUMECTANT, FRAGRANCE, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING | 0 · 0 | Green |
| PEG/PPG-8/3 Laurate | SURFACTANT - EMULSIFYING, EMULSION STABILISING, HAIR CONDITIONING, HUMECTANT, SURFACTANT - CLEANSING | 0 · 0 | Green |
| Pentylene Glycol | SKIN CONDITIONING, SOLVENT | 0 · 0 | Green |
| Polyglyceryl-4 Caprate | SURFACTANT - EMULSIFYING | 0 · – | Green |
| 1,2-Hexanediol | SKIN CONDITIONING, SOLVENT | 0 · 0 | Green |
| Niacinamide | SMOOTHING | 0 · 0 | Green |
| Epigallocatechin Gallatyl Glucoside | ANTIOXIDANT, SKIN CONDITIONING | 0 · – | Green |
| Hydrolyzed Hyaluronic Acid | HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING | 0 · 0 | Green |
| Allantoin | SKIN CONDITIONING, SKIN PROTECTING, SOOTHING | 0 · 0 | Green |
| Tocopheryl Acetate | ANTIOXIDANT, SKIN CONDITIONING | 0 · 0 | Green |
| Ammonium Acryloyldimethyltaurate/VP Copolymer | VISCOSITY CONTROLLING | 0 · 0 | Green |
| Sodium Hyaluronate | HUMECTANT, SKIN CONDITIONING | 0 · 0 | Green |
| Tocopherol | ANTIOXIDANT, FRAGRANCE, SKIN CONDITIONING - MISCELLANEOUS, SKIN CONDITIONING - OCCLUSIVE | 0 · 0 | Green |
| Sodium Gluconate | CHELATING, SKIN CONDITIONING | 0 · 0 | Green |
| Citric Acid | BUFFERING, CHELATING, FRAGRANCE | 1 · 0 | Green |
Ingredients explained
- Water
- Primary solvent and base; requires preservative system to prevent microbial growth
- Butylene Glycol
- Polyol humectant and solvent at 1–5%; aids solubilization, light feel
- PEG/PPG-8/3 Laurate
- Nonionic surfactant for emulsification/cleansing; mild, but PEG on damaged skin needs care.
- Pentylene Glycol
- Polyol humectant at 1-3%; low irritancy, suitable for sensitive skin
- Polyglyceryl-4 Caprate
- Non-ionic emulsifier; biodegradable, compatibility with anionics requires check.
- 1,2-Hexanediol
- Polyol solvent and preservative booster at 1–5%; light feel, can replace some traditional preservatives
- Niacinamide
- Niacinamide at 2–5%; improves texture, controls oil, brightens; high levels may cause sensitivity
- Epigallocatechin Gallatyl Glucoside
- Tea polyphenol analog; antioxidant & skin conditioning
- Hydrolyzed Hyaluronic Acid
- Low-MW humectant with superior penetration vs high-MW; 0.1-0.5% typical, hygroscopic, store dry to prevent clumping.
- Allantoin
- Skin soother at 0.5-2%; promotes cell regeneration
- Tocopheryl Acetate
- Vitamin E derivative antioxidant at 0.1–1%; more stable than tocopherol, store protected from light
- Ammonium Acryloyldimethyltaurate/VP Copolymer
- Cationic polymer providing suspension, thickening, and conditioning; often paired with anionic thickening systems, low usage, imparts slip.
- Sodium Hyaluronate
- Potent humectant at 0.1–2%; different MW for penetration depth, high levels may draw moisture
- Tocopherol
- Natural antioxidant (vitamin E) at 0.1–1%; prone to oxidation, store protected from light
- Sodium Gluconate
- Mild chelator, aids skin conditioning; typically used at low levels as auxiliary
- Citric Acid
- Buffer and chelator at 0.1–2%; adjusts pH, may irritate sensitive skin at low pH
Source: full ingredient list published on the product label, collected 2026-09-17. Ratings are our internal reading, not a regulatory conclusion. · Product page
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