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GlobalSerum

Cetaphil advanced daily defence serum

Cetaphil cetaphil advanced daily defence serum lists 16 ingredients on its label, 16 decoded. See what each one does, its irritancy and comedogenic tendency, and its status in national inventories.

Ingredients overview

Label order. Colour is our internal rating: green routine, yellow restricted or worth a look, red prohibited or high-risk, grey not yet decoded.

Ingredients are listed in label order; the order reflects the label only, not exact concentrations.

  1. Water
  2. Butylene Glycol
  3. PEG/PPG-8/3 Laurate
  4. Pentylene Glycol
  5. Polyglyceryl-4 Caprate
  6. 1,2-Hexanediol
  7. Niacinamide
  8. Epigallocatechin Gallatyl Glucoside
  9. Hydrolyzed Hyaluronic Acid
  10. Allantoin
  11. Tocopheryl Acetate
  12. Ammonium Acryloyldimethyltaurate/VP Copolymer
  13. Sodium Hyaluronate
  14. Tocopherol
  15. Sodium Gluconate
  16. Citric Acid

Highlights

Free of alcoholFree of fragranceFree of parabensFree of siliconesFree of sulfatesFree of mineral oilFree of essential oilsFree of formaldehyde releasersContains PEG

Formulation view Water-based serum. Polyol solvent system for actives. Niacinamide for clarity, EGCG and hyaluronic acids for moisture, allantoin and tocopherol for soothing. Oil-free, lightweight texture. Suited for combination or oily skin. Factory note: Preservative-free system relies on polyols and chelants; strict microbial control is essential.

Key ingredients

ANTIPLAQUE
Water
HUMECTANT
Butylene Glycol
SURFACTANT - EMULSIFYING
PEG/PPG-8/3 LauratePolyglyceryl-4 Caprate
SKIN CONDITIONING
Pentylene Glycol1,2-Hexanediol
SMOOTHING
Niacinamide
ANTIOXIDANT
Epigallocatechin Gallatyl Glucoside

Other ingredients

Hydrolyzed Hyaluronic AcidAllantoinTocopheryl AcetateAmmonium Acryloyldimethyltaurate/VP CopolymerSodium HyaluronateTocopherolSodium GluconateCitric Acid

Skim through

IngredientWhat it doesIrr. · Com.Rating
WaterANTIPLAQUE, SKIN CONDITIONING, SOLVENT0 · 0Green
Butylene GlycolHUMECTANT, FRAGRANCE, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING0 · 0Green
PEG/PPG-8/3 LaurateSURFACTANT - EMULSIFYING, EMULSION STABILISING, HAIR CONDITIONING, HUMECTANT, SURFACTANT - CLEANSING0 · 0Green
Pentylene GlycolSKIN CONDITIONING, SOLVENT0 · 0Green
Polyglyceryl-4 CaprateSURFACTANT - EMULSIFYING0 · –Green
1,2-HexanediolSKIN CONDITIONING, SOLVENT0 · 0Green
NiacinamideSMOOTHING0 · 0Green
Epigallocatechin Gallatyl GlucosideANTIOXIDANT, SKIN CONDITIONING0 · –Green
Hydrolyzed Hyaluronic AcidHAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING0 · 0Green
AllantoinSKIN CONDITIONING, SKIN PROTECTING, SOOTHING0 · 0Green
Tocopheryl AcetateANTIOXIDANT, SKIN CONDITIONING0 · 0Green
Ammonium Acryloyldimethyltaurate/VP CopolymerVISCOSITY CONTROLLING0 · 0Green
Sodium HyaluronateHUMECTANT, SKIN CONDITIONING0 · 0Green
TocopherolANTIOXIDANT, FRAGRANCE, SKIN CONDITIONING - MISCELLANEOUS, SKIN CONDITIONING - OCCLUSIVE0 · 0Green
Sodium GluconateCHELATING, SKIN CONDITIONING0 · 0Green
Citric AcidBUFFERING, CHELATING, FRAGRANCE1 · 0Green

Ingredients explained

Water
Primary solvent and base; requires preservative system to prevent microbial growth
Butylene Glycol
Polyol humectant and solvent at 1–5%; aids solubilization, light feel
PEG/PPG-8/3 Laurate
Nonionic surfactant for emulsification/cleansing; mild, but PEG on damaged skin needs care.
Pentylene Glycol
Polyol humectant at 1-3%; low irritancy, suitable for sensitive skin
Polyglyceryl-4 Caprate
Non-ionic emulsifier; biodegradable, compatibility with anionics requires check.
1,2-Hexanediol
Polyol solvent and preservative booster at 1–5%; light feel, can replace some traditional preservatives
Niacinamide
Niacinamide at 2–5%; improves texture, controls oil, brightens; high levels may cause sensitivity
Epigallocatechin Gallatyl Glucoside
Tea polyphenol analog; antioxidant & skin conditioning
Hydrolyzed Hyaluronic Acid
Low-MW humectant with superior penetration vs high-MW; 0.1-0.5% typical, hygroscopic, store dry to prevent clumping.
Allantoin
Skin soother at 0.5-2%; promotes cell regeneration
Tocopheryl Acetate
Vitamin E derivative antioxidant at 0.1–1%; more stable than tocopherol, store protected from light
Ammonium Acryloyldimethyltaurate/VP Copolymer
Cationic polymer providing suspension, thickening, and conditioning; often paired with anionic thickening systems, low usage, imparts slip.
Sodium Hyaluronate
Potent humectant at 0.1–2%; different MW for penetration depth, high levels may draw moisture
Tocopherol
Natural antioxidant (vitamin E) at 0.1–1%; prone to oxidation, store protected from light
Sodium Gluconate
Mild chelator, aids skin conditioning; typically used at low levels as auxiliary
Citric Acid
Buffer and chelator at 0.1–2%; adjusts pH, may irritate sensitive skin at low pH

Source: full ingredient list published on the product label, collected 2026-09-17. Ratings are our internal reading, not a regulatory conclusion. · Product page

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